New podcast on our work: “Why Vaccines Behave Differently in Cancer Patients.”

Vaccines usually follow a clear script—stimulate the immune system, build protection, end of story. But in cancer patients, that script gets rewritten. Immune responses can be weaker, stronger, or simply different from what clinicians expect.

In the latest episode of “The Code of Life”, Florian explores why this happens and how modern tools are helping researchers understand the immune system under the unique pressures of cancer and its treatments.

Cancer and therapy reshape immune pathways in ways that make standard vaccine responses less predictable. These shifts aren’t random; they provide clues about how immunity adapts—or struggles to adapt—during disease. Understanding those patterns can help refine vaccines and immunotherapies for patients whose biology doesn’t fit the norm.

The episode highlights how Florian and the Systems Immunology Lab use a range of models, from clinical samples to organoids—small, 3D lab‑grown tissues that mimic simplified lymph nodes-to computational models to better understand vaccine responses in cancer patients.

🎧 Listen to the episode (in German): https://codedeslebens.podigee.io/50-krebs-impfung-immunsystem
🎙 Podcast overview: https://codedeslebens.podigee.io